Wild Bio raises $60m to supercharge photosynthesis with AI-powered precision breeding

Wild Bioscience co-founders Dr. Ross Hendron (left) and Prof. Steve Kelly.
Wild Bioscience co-founders Dr. Ross Hendron (left) and Prof. Steve Kelly. (Wild Bioscience)

UK start-up says its breakthrough platform could unlock yield gains in major crops by mimicking evolution and enhancing photosynthesis – now the challenge is scaling it for global seed partners

Wild Bioscience has raised $60 million (£45m) in Series A funding to accelerate the development of its AI-driven precision breeding platform. The Oxford University spinout, co-founded by evolutionary biologists Dr. Ross Hendron and Prof. Steve Kelly, is using custom-built algorithms to identify and activate beneficial traits in crops by simulating how evolution might have taken a different path.

The company essentially is trying to “replay the tape of life” to see how crops like wheat could have evolved with better traits, Hendron told AgTechNavigator. The company can’t run fast evolution experiments in plants, he explained, so it simulates them using large, diverse datasets, most of which it generates itself.

Cracking the photosynthesis code

Wild Bio’s flagship breakthrough is in improving photosynthetic efficiency – a notoriously complex trait that has long eluded traditional breeding and biotech approaches. The company has built a proprietary dataset that maps hundreds of potential limitations in photosynthesis and links them to genetic and physiological data.

Field trials in the UK, Brazil, Argentina, and the US in the UK have so far seen double-digit improvements, Hendron said. “We’re still testing over larger areas and varieties. But we see when we’re improving photosynthesis, we do see a benefit in early vigour – so the plants grow faster in those early stages.”

Field trials in the UK, Brazil, Argentina, and the US in the UK have so far seen double-digit improvements soybean, wheat, and maize.
Field trials in the UK, Brazil, Argentina, and the US in the UK have so far seen double-digit improvements soybean, wheat, and maize. (DAVID J CASEBOW/Wild Bio)

From lab to field – and into the hands of seed companies

The company’s gene editing approach, typically using CRISPR, allows it to replicate beneficial traits found in wild species and introduce them into commercial crops. Wild Bio is currently focused on soybean, wheat, and maize – broad-acre crops where even small gains can have a major environmental and economic impact.

While photosynthesis is the most advanced trait in its pipeline, Wild Bio is also exploring drought resilience and a novel carbon removal programme that encourages plants to sequester carbon as inorganic matter underground.

The company has begun partnering with global seed companies, particularly row crop providers in North and South America, though no deals have been publicly announced yet. “They recognise this is a complimentary approach to what they’re doing and a unique way of going about this,” Hendron said.

“Wild Bio is using AI to better understand the lessons learned over millions of years of evolution encoded in plant genomes. Those insights combined with precision breeding has enabled Wild Bio to develop new varieties of crops with both higher yields and climate resilience. The ultimate goal is to grow these new crop varieties on a commercial scale and help provide food security around the world. EIT is committed to working with Wild Bio to reach this goal.”
Larry Ellison, CTO and chairman of Oracle and Founder of the Ellison Institute of Technology, said: “Wild Bio is using AI to better understand the lessons learned over millions of years of evolution encoded in plant genomes. Those insights combined with precision breeding has enabled Wild Bio to develop new varieties of crops with both higher yields and climate resilience. The ultimate goal is to grow these new crop varieties on a commercial scale and help provide food security around the world. EIT is committed to working with Wild Bio to reach this goal.” (Steve Walker /Oracle PR from Redwood Shores, Calif., USA, CC BY 2.0 , via Wikimedia Commons)

Scaling the science

The $60 million Series A round, led by the Ellison Institute of Technology, will fund expanded R&D, more field trials, team growth, and commercialisation efforts. Hendron said the Ellison Institute’s long-term, strategic mindset was a key factor in choosing them as lead investor.

“This isn’t a SaaS model with a two-year turnaround,” he said. “We needed investors who understand the scientific risks and timelines.”

One of the biggest technical hurdles remains time. “You can’t compress a year-long field trial,” Hendron noted. The company is investing heavily in early-stage screening and high-throughput data collection to make better predictions before hitting the field.

Replaying the tape of evolution: The Wild Bio platform deciphers hundreds of millions of years of plant evolution to identify promising genetic improvements from wild species. These evolutionary innovations are then used to guide precision breeding strategies for modern elite crop varieties.
Replaying the tape of evolution: The Wild Bio platform deciphers hundreds of millions of years of plant evolution to identify promising genetic improvements from wild species. These evolutionary innovations are then used to guide precision breeding strategies for modern elite crop varieties. (ALEX BEDWELL/Wild Bio)

A globally scalable solution

What makes Wild Bio’s platform especially compelling, Hendron argues, is its scalability. “There are billion farmers on the planet; they’ve all got seeds.” If it can load a solution into the seed, it doesn’t matter whether the farmer is in a high-tech cornfield in Iowa or a subsistence farm in rural Africa – it will simply works, requiring no infrastructure change or behaviour change. “The whole point is that the seed is going to perform better for you regardless of the farming system.”